Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.74 |
| ▸ | MEN1 | O00255 | 10/20 | 0.74 |
| ▸ | POLB | P06746 | 4/20 | 0.74 |
| ▸ | USP2 | O75604 | 8/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484431 | 0.85 | KMT2A (1.00) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL19423810 | 0.84 | KMT2A (0.74) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL24784337 | 0.81 | KMT2A (0.70) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL10313084 | 0.81 | KMT2A (0.70) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL28085238 | 0.81 | KMT2A (0.70) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL31094030 | 0.81 | MEN1 (0.69) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL26053794 | 0.81 | MEN1 (0.69) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL12581330 | 0.80 | KMT2A (1.00) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL3502868 | 0.78 | MEN1 (0.66) | KMT2AMEN1POLBUSP2KEAP1 | |
| SCHEMBL30870383 | 0.78 | MEN1 (0.66) | KMT2AMEN1POLBUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150268246-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC | 2015-09-24 | — | — | US | disclosed |
| US-9034655-B2 | Highly water-soluble, cationic luminescent labels | SETA BIOMEDICALS, LLC (US) | 2015-05-19 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20110143387-A1 | HIGHLY WATER-SOLUBLE, CATIONIC LUMINESCENT LABELS | SETA BIOMEDICALS, LLC | 2011-06-16 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20080076188-A1 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | PTMS, IK, PHAX | KMT2A 4753/4885MEN1 3976/4885POLB 4198/4885 |
| US-20080076188-A1 | Luminescent compounds | REL, QRFPR, RCOR3 | KMT2A 3049/4885MEN1 3074/4885POLB 2187/4885 |
| US-20110143387-A1 | HIGHLY WATER-SOLUBLE, CATIONIC LUMINESCENT LABELS | SLC7A5, ABCG2, SLC43A1 | KMT2A 3800/4885MEN1 880/4885POLB 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.