Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17745706 | 1.00 | KMT2A (0.39) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL21799353 | 1.00 | KMT2A (0.39) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL26529 | 1.00 | KMT2A (0.39) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL20357288 | 1.00 | KMT2A (0.39) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL9418339 | 0.90 | MEN1 (0.34) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL15826282 | 0.87 | KMT2A (0.32) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL444447 | 0.86 | EPHX2 (0.38) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL3778927 | 0.84 | ALDH1A1 (0.32) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL29272738 | 0.83 | EPHX2 (0.39) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 | |
| SCHEMBL8157774 | 0.83 | MEN1 (0.35) | KMT2ACYP2C19MEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-3004050-A1 | CYANOSTILBENES | Rolic AG (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | KMT2A 3167/4885CYP2C19 169/4885MEN1 3329/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | KMT2A 2902/4885CYP2C19 4469/4885MEN1 4064/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | KMT2A 2902/4885CYP2C19 4469/4885MEN1 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.