SCHEMBL20299221

SCHEMBL20299221

Cn1nnc(N2C(=O)C=CC2=O)n1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
FAAH O00519 2/20 0.34
CCR9 P51686 1/20 0.34
HSP90AA1 P07900 1/20 0.33
CCR6 P51684 1/20 0.33
BCHE P06276 1/20 0.33
TSHR P16473 2/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TLR9 Q9NR96 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5178729 0.66 MGLL (0.48) MGLLGSK3AGSK3BFAAHHSP90AA1
SCHEMBL5606239 0.61 BCHE (0.44) MGLLFAAHHSP90AA1CCR6BCHE
SCHEMBL327659 0.59 MGLL (0.40) MGLLGSK3AGSK3BFAAHHSP90AA1
SCHEMBL1706734 0.59 BCHE (0.43) MGLLGSK3AGSK3BFAAHHSP90AA1
SCHEMBL36966 0.57
SCHEMBL30003370 0.55 MGLL (0.40) MGLLFAAHHSP90AA1CCR6BCHE
SCHEMBL19511786 0.55 MGLL (0.48) MGLLGSK3AGSK3BFAAHHSP90AA1
SCHEMBL3163923 0.54 MGLL (0.34) MGLLFAAHBCHETSHRTLR9
SCHEMBL95324 0.53 MGLL (1.00) MGLLFAAHHSP90AA1CCR6BCHE
SCHEMBL8641616 0.53 MGLL (0.70) MGLLFAAHHSP90AA1CCR6BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558976-A1 SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer CropScience Aktiengesellschaft (DE) 2019-10-30 EP disclosed
WO-2018114663-A1 SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-06-28 WO disclosed