SCHEMBL20299863

SCHEMBL20299863

COC(=O)N(C1c2ccccc2-c2ccccc21)[C@H](C(=O)O)C(C)NC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.40
▸ GABRB1 P18505 1/20 0.36
▸ GABRB2 P47870 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ PPARA Q07869 5/20 0.36
▸ PPARG P37231 4/20 0.36
▸ CTSK P43235 4/20 0.35
▸ CTSS P25774 3/20 0.35
▸ ATM Q13315 1/20 0.35
▸ ACE P12821 1/20 0.35
▸ APP P05067 2/20 0.35
▸ PPARD Q03181 2/20 0.35
▸ CTSL P07711 1/20 0.34
▸ CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19580400 0.82 KEAP1 (0.35) ATM
SCHEMBL4343962 0.82 KEAP1 (0.35) ATM
SCHEMBL25183055 0.81 GPR3 (0.38) MAPTATM
SCHEMBL25182326 0.81 GPR3 (0.38) MAPTATM
SCHEMBL28669006 0.80 ABCB1 (0.36) IDO1
SCHEMBL28669009 0.80 ABCB1 (0.36) IDO1
SCHEMBL30510269 0.80 GPR3 (0.41) MAPTATM
SCHEMBL1830100 0.80 GPR3 (0.41) MAPTATM
SCHEMBL30510362 0.80 GPR3 (0.41) MAPTATM
SCHEMBL4603276 0.80 GPR3 (0.41) MAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570317-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2025-06-18 — — EP disclosed
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2023-01-05 — — US disclosed
US-11406617-B2 Compounds for the treatment of bovine or swine respiratory disease INTERVET INC. (US) 2022-08-09 — — US disclosed
US-20200085779-A1 Compounds for the Treatment of Bovine or Swine Respiratory Disease INTERVET INC. (US) 2020-03-19 — — US disclosed
EP-3558284-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2019-10-30 — — EP disclosed
WO-2018115432-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INTERNATIONAL B.V. (NL) 2018-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11406617-B2 Compounds for the treatment of bovine or swine respiratory disease PIGS, BTD, PPARD IDO1 1321/4885GABRB1 836/4885GABRB2 1001/4885
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE PIGS, BTD, BRD1 IDO1 1873/4885GABRB1 1062/4885GABRB2 1226/4885
US-20200085779-A1 Compounds for the Treatment of Bovine or Swine Respiratory Disease PIGS, BTD, PPARD IDO1 1321/4885GABRB1 836/4885GABRB2 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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