Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20302471 | 1.00 | USP2 (0.54) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL21652255 | 0.74 | USP2 (0.67) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL23367923 | 0.73 | USP2 (0.74) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL6602234 | 0.70 | USP2 (0.69) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL20301834 | 0.67 | ABCG2 (0.38) | USP2LMNAMEN1KMT2ANPC1 | |
| SCHEMBL7043652 | 0.67 | LMNA (1.00) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL20301955 | 0.66 | LMNA (0.36) | HTTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7972108 | 0.66 | LMNA (0.84) | USP2HTTLMNAPOLBGAA | |
| SCHEMBL11543815 | 0.63 | LMNA (0.61) | USP2LMNAPOLBGAATDP1 | |
| SCHEMBL14006485 | 0.62 | LMNA (0.58) | USP2HTTLMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116073-A1 | 1, 2, 3-THIADIAZOLE COMPOUNDS AND THEIR USE AS CROP PROTECTING AGENT | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |