Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306539 | 0.66 | MEN1 (0.37) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL25795143 | 0.66 | MEN1 (0.42) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL9037805 | 0.64 | KMT2A (0.36) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL2776823 | 0.63 | TSHR (0.47) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL20263429 | 0.62 | CRBN (0.48) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL20263428 | 0.62 | CRBN (0.48) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL30720904 | 0.62 | PDE3B (0.32) | — | |
| SCHEMBL13104453 | 0.62 | TSHR (0.42) | MEN1TSHRCYP2C19RAB9AKMT2A | |
| SCHEMBL31634014 | 0.61 | DRD2 (0.30) | — | |
| SCHEMBL29569183 | 0.61 | KMT2A (0.67) | MEN1TSHRRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559005-A1 | THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | Biotheryx Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018118947-A1 | THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. (US) | 2018-06-28 | — | — | WO | disclosed |