Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795143 | 0.71 | MEN1 (0.42) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL1822840 | 0.71 | PNMT (0.39) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL16870185 | 0.70 | CES1 (0.34) | MEN1KMT2ATSHRCYP2C19ALDH1A1 | |
| SCHEMBL20304585 | 0.66 | MEN1 (0.39) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL3919487 | 0.66 | MEN1 (0.32) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL13600312 | 0.66 | MEN1 (0.30) | MEN1KMT2APNMTALDH1A1MAPT | |
| SCHEMBL2915061 | 0.65 | PNMT (0.34) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL8342683 | 0.64 | PTK2 (0.33) | TRIM24 | |
| SCHEMBL27398202 | 0.64 | MEN1 (0.51) | MEN1KMT2ATSHRCYP2C19RAB9A | |
| SCHEMBL9918979 | 0.64 | METAP1 (0.50) | MEN1KMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064842-A1 | AMIDE AND ESTER MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |