Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759348 | 0.80 | MAPK1 (0.53) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL20953573 | 0.78 | CDK2 (0.50) | PDGFRBPDGFRARAB9AMAPTMEN1 | |
| SCHEMBL16125091 | 0.78 | PDGFRB (0.46) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL17676271 | 0.78 | PDGFRB (0.46) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL16125096 | 0.78 | ALDH1A1 (0.51) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL20305884 | 0.77 | MAPT (0.52) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL3637143 | 0.77 | PIK3CA (0.55) | PDGFRBPDGFRARAB9AKMT2AMAPK1 | |
| SCHEMBL18768864 | 0.75 | PDGFRB (0.58) | PDGFRBPDGFRARAB9AMAPTKDM4E | |
| SCHEMBL4697024 | 0.75 | MAPK1 (0.56) | PDGFRBPDGFRAMAPK1ATMPIK3CA | |
| Hydrochloric Acid SCHEMBL5623610 | 0.74 | MAPK1 (0.55) | PDGFRBPDGFRAMAPK1ATMPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004733-B2 | — | — | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004733-B2 | — | SDHB, SDHA, NDUFS5 | PDGFRB 1274/4885PDGFRA 1727/4885RAB9A 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.