SCHEMBL2030717

SCHEMBL2030717

CCCCc1ccc(O)c(-n2nc3ccc(C(=O)O)cc3n2)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.46
KAT8 Q9H7Z6 2/20 0.45
MPL P40238 1/20 0.43
PPARA Q07869 1/20 0.42
AGTR1 P30556 2/20 0.41
AGTR2 P50052 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RARA P10276 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
HCAR3 P49019 2/20 0.41
PLA2G4A P47712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699390 0.87 KDM4E (0.40) MEN1ALDH1A1MAPTKMT2AHCAR3
SCHEMBL13700389 0.84 MEN1 (0.41) MEN1ALDH1A1MAPTKMT2AHCAR3
SCHEMBL429864 0.82 NPC1 (0.57) KAT8ALDH1A1MAPT
SCHEMBL29431672 0.82 NPC1 (0.57) KAT8ALDH1A1MAPT
SCHEMBL2401376 0.82 MYC (0.51) MEN1ALDH1A1MAPTKMT2AHCAR3
SCHEMBL2589692 0.82 NPC1 (0.42) KAT8MEN1MAPTKMT2A
SCHEMBL28907380 0.80 CA2 (0.40) KAT8MEN1MAPTKMT2A
SCHEMBL17785947 0.79 LMNA (0.54) KAT8PPARAALDH1A1
SCHEMBL28875109 0.79 LMNA (0.54) KAT8PPARAALDH1A1
SCHEMBL27466288 0.79 NPC1 (0.39) KAT8MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-20060216437-A1 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-09-28 US disclosed