SCHEMBL20308264

SCHEMBL20308264

Sc1cccc2oc3cnccc3c12

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 13/20 0.40
IDO1 P14902 8/20 0.40
ROCK2 O75116 2/20 0.36
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPKAPK2 P49137 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20172160 0.86 KDM4E (0.33) TDO2IDO1LMNACYP1A2CYP3A4
SCHEMBL17115248 0.81 TDO2 (0.41) TDO2IDO1ROCK2LMNACYP1A2
SCHEMBL17490043 0.79 LMNA (0.50) TDO2IDO1LMNACYP1A2CYP3A4
SCHEMBL27401128 0.79 TDO2 (0.40) TDO2IDO1ROCK2LMNACYP1A2
SCHEMBL20308260 0.79 TDO2 (0.43) TDO2IDO1ROCK2LMNACYP1A2
SCHEMBL24056383 0.79 TDO2 (0.46) TDO2IDO1ROCK2
SCHEMBL7974384 0.79 TDO2 (0.40) TDO2IDO1ROCK2
SCHEMBL23947329 0.79 TDO2 (0.40) TDO2IDO1LMNACYP1A2CYP3A4
SCHEMBL19051921 0.79 IDO1 (0.42) TDO2IDO1ROCK2LMNACYP3A4
SCHEMBL21237825 0.78 IDO1 (0.43) TDO2IDO1ROCK2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339395-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2019-10-02 EP disclosed
EP-3339395-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2018-06-27 EP disclosed