SCHEMBL7974384

SCHEMBL7974384

Cc1cccc2oc3cnccc3c12

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 13/20 0.40
IDO1 P14902 10/20 0.40
ELANE P08246 1/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ROCK2 O75116 1/20 0.36
BRAF P15056 1/20 0.36
EIF2AK3 Q9NZJ5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22373914 0.86 ELANE (0.38) TDO2IDO1ELANEALDH1A1MAPT
SCHEMBL17115248 0.81 TDO2 (0.41) TDO2IDO1ALDH1A1SMN1; SMN2ROCK2
SCHEMBL17490043 0.79 LMNA (0.50) TDO2IDO1
SCHEMBL27401128 0.79 TDO2 (0.40) TDO2IDO1ROCK2
SCHEMBL20308260 0.79 TDO2 (0.43) TDO2IDO1ROCK2
SCHEMBL23947329 0.79 TDO2 (0.40) TDO2IDO1
SCHEMBL19051921 0.79 IDO1 (0.42) TDO2IDO1ALDH1A1MAPTKMT2A
SCHEMBL24056383 0.79 TDO2 (0.46) TDO2IDO1ROCK2BRAFEIF2AK3
SCHEMBL20308264 0.79 TDO2 (0.40) TDO2IDO1ROCK2
SCHEMBL21237825 0.78 IDO1 (0.43) TDO2IDO1ELANEROCK2BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
WO-2009147476-A1 NOVEL PDE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION MATRIX LABORATORIES LTD. (IN) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 TDO2 4168/4885IDO1 3021/4885ELANE 1569/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 TDO2 4168/4885IDO1 3021/4885ELANE 1569/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 TDO2 122/4885IDO1 623/4885ELANE 2540/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 TDO2 4168/4885IDO1 3021/4885ELANE 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.