SCHEMBL2031146

SCHEMBL2031146

c1ccc(OC(OC(Oc2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.41
TSHR P16473 2/20 0.39
LTA4H P09960 1/20 0.39
SCN4A P35499 2/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
SRD5A2 P31213 1/20 0.36
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
CA4 P22748 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KCNK2 O95069 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1C Q13936 1/20 0.36
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564026 0.90 SLC6A4 (0.44) SLC6A4TSHRLTA4HSCN4AADRA2A
SCHEMBL10689396 0.85 SLC6A4 (0.49) SLC6A4SLC6A2SLC6A3KCNK2KCNH2
SCHEMBL1582082 0.85 NPSR1 (0.42) TSHR
SCHEMBL5067019 0.85 SLC6A4 (0.49) SLC6A4ADRA2ASRD5A2SLC6A2SLC6A3
SCHEMBL18297906 0.81 SLC6A4 (0.39) SLC6A4TSHRLTA4HSCN4AADRA2A
SCHEMBL10942730 0.81 SLC6A4 (0.39) SLC6A4TSHRLTA4HSCN4AADRA2A
SCHEMBL8518703 0.81 SLC6A4 (0.39) SLC6A4TSHRLTA4HSCN4AADRA2A
SCHEMBL2035765 0.81 CA4 (0.44) SLC6A4TSHRLTA4HSCN4AADRA2A
SCHEMBL10346994 0.80 SLC6A4 (0.33) SLC6A4SCN4AADRA2AADRA2BADRA2C
SCHEMBL16382776 0.78 NPSR1 (0.47) SLC6A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998017277-A1 AMIDINE COMPOUNDS FOR USE IN SYSTEMIC TREATING ECTO AND/OR ENDO PARASITIC DISEASES VIRBAC S.A. (FR) 1998-04-30 WO claimed
EP-0836851-A1 Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions VIRBAC S.A. (FR) 1998-04-22 EP claimed
JP-5155799-A None JP disclosed
CN-113444111-A Novel benzodiazepine derivative and use thereof 尹图赛利有限公司 2021-09-28 CN disclosed
CN-109438317-B Preparation method of nitrogen-alkyl (deuterated alkyl) aromatic heterocycle and alkyl (deuterated alkyl) aryl ether compound 武汉大学 2021-04-02 CN disclosed
CN-207941219-U A kind of 2- (4- ethoxyl phenenyls) -2- methyl-propyl -3- phenoxy benzyl ether desolventizing equipments 连云港市国盛化工有限公司 2018-10-09 CN disclosed
US-RE44354-E1 Amyloid plaque aggregation inhibitors and diagnostic imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-07-09 US disclosed
US-RE44338-E1 Amyloid plaque aggregation inhibitors and diagnostic imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-07-02 US disclosed
JP-2011128217-A OPTICAL DROP CABLE HITACHI CABLE LTD 2011-06-30 JP disclosed
CN-100422180-C Amyloid plaque aggregation inhibitors and diagnostic imaging agents UNIV PENNSYLVANIA (US) 2008-10-01 CN disclosed
US-7425318-B2 Amyloid plaque aggregation inhibitors and diagnostic imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2008-09-16 US disclosed
US-5665763-A ANTIPICORNAVIRAL AGENTS SANOFI, S.A. (FR) 1997-09-09 US disclosed
US-5567717-A COMBATTING PICORNAVIRUSES STERLING WINTHROP, INC. (US) 1996-10-22 US disclosed
US-5514679-A TREATMENT OF PICORNAVIRUS INFECTIONS STERLING WINTHROP INC. (US) 1996-05-07 US disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995031439-A1 THERAPEUTIC PHENOXYALKYLPYRIDAZINES AND INTERMEDIATES THEREFOR SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed
JP-H05155799-A METHOD FOR PURIFYING P-HALODIFLUOROMETHOXYNEOPHYL M-PHENOXYBENZYL ETHERS MITSUI TOATSU CHEM INC 1993-06-22 JP disclosed
EP-0437784-A1 Imidazolidine derivatives, process for producing the same and pesticides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-07-24 EP disclosed
EP-0421385-A1 Process for producing p-hydroxyneophyl m-phenoxybenzyl ether MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-10 EP disclosed