SCHEMBL18297906

SCHEMBL18297906

[SiH3]OC(Oc1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.39
SCN4A P35499 2/20 0.36
TSHR P16473 2/20 0.36
LTA4H P09960 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SRD5A2 P31213 1/20 0.34
DPP4 P27487 2/20 0.33
F2 P00734 1/20 0.33
CHRM1 P11229 1/20 0.33
CA4 P22748 1/20 0.33
POLB P06746 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564026 0.85 SLC6A4 (0.44) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL2031146 0.81 SLC6A4 (0.41) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL10942730 0.77 SLC6A4 (0.39) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL8518703 0.77 SLC6A4 (0.39) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL2035765 0.77 CA4 (0.44) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL18297941 0.74 THRB (0.41) TSHRDPP4F2CA4
SCHEMBL16382776 0.74 NPSR1 (0.47) SLC6A4TSHR
SCHEMBL11666723 0.72 SLC6A4 (0.36) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL7644220 0.72 SLC6A4 (0.36) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL8717190 0.71 LMNA (0.42) SLC6A4TSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103805-B1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND AIST (JP) 2020-11-18 EP disclosed
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-06-29 US disclosed
EP-3103805-A1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND National Institute of Advanced Industrial Science and Technology (JP) 2016-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound LSS, MSMO1, ALG3 SLC6A4 4216/4885SCN4A 2186/4885TSHR 4865/4885
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound LSS, MSMO1, ALG3 SLC6A4 4216/4885SCN4A 2186/4885TSHR 4865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.