SCHEMBL8518703

SCHEMBL8518703

[C]OC(Oc1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.39
SCN4A P35499 2/20 0.36
TSHR P16473 2/20 0.36
LTA4H P09960 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SRD5A2 P31213 1/20 0.34
DPP4 P27487 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
F2 P00734 1/20 0.33
CHRM1 P11229 1/20 0.33
CA4 P22748 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564026 0.85 SLC6A4 (0.44) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL2031146 0.81 SLC6A4 (0.41) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL18297906 0.77 SLC6A4 (0.39) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL2035765 0.77 CA4 (0.44) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL10942730 0.77 SLC6A4 (0.39) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL16382776 0.74 NPSR1 (0.47) SLC6A4TSHR
SCHEMBL11666723 0.72 SLC6A4 (0.36) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL7644220 0.72 SLC6A4 (0.36) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL9180659 0.71 SCN4A (0.43) SLC6A4SCN4ATSHRLTA4HADRA2A
SCHEMBL8309561 0.71 LTA4H (0.35) SLC6A4SCN4ATSHRLTA4HADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915657-A1 AQUEOUS INSECTICIDE AND PESTICIDE COMPOSITION, METHOD OF PRODUCTION AND USE THEREOF Attali, Jean-Claude (FR) 1999-05-19 EP disclosed
WO-1997047198-A1 AQUEOUS INSECTICIDE AND PESTICIDE COMPOSITION, METHOD OF PRODUCTION AND USE THEREOF ATTALI JEAN CLAUDE (FR) 1997-12-18 WO disclosed