Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140486 | 0.91 | GRM5 (0.32) | MEN1KMT2A | |
| SCHEMBL22140445 | 0.76 | NOTUM (0.34) | ALDH1A1HPGDMEN1GAAMAPT | |
| SCHEMBL29346297 | 0.69 | TNKS (0.33) | TNKSPARP1TNKS2ALDH1A1HPGD | |
| SCHEMBL22306573 | 0.69 | KMT2A (0.44) | ALDH1A1HPGDMEN1GAAMAPT | |
| SCHEMBL9184240 | 0.68 | PARP1 (0.51) | TNKSPARP1TNKS2ALDH1A1HPGD | |
| SCHEMBL6785941 | 0.67 | GRIA1 (0.50) | TNKSPARP1TNKS2 | |
| SCHEMBL20312991 | 0.67 | ALDH1A1 (0.43) | TNKSPARP1TNKS2ALDH1A1HPGD | |
| SCHEMBL2095934 | 0.66 | ALDH1A1 (0.41) | TNKSPARP1TNKS2ALDH1A1HPGD | |
| SCHEMBL8276444 | 0.63 | NOTUM (0.50) | TNKSPARP1TNKS2ALDH1A1HPGD | |
| SCHEMBL28466766 | 0.61 | TNKS (0.46) | TNKSPARP1TNKS2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
| US-10717751-B2 | Near-IR glucose sensors | PROFUSA, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | TNKS 2255/4885PARP1 3760/4885TNKS2 1937/4885 |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | TNKS 2255/4885PARP1 3760/4885TNKS2 1937/4885 |
| US-10717751-B2 | Near-IR glucose sensors | IRS1, G6PD, SLC2A8 | TNKS 3673/4885PARP1 2320/4885TNKS2 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.