Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | EYA2 | O00167 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666026 | 0.75 | PSMB5 (0.36) | EYA2APPACETDP1 | |
| SCHEMBL23893966 | 0.73 | ALDH1A1 (0.36) | CYP1A2EYA2APPACETDP1 | |
| SCHEMBL17666038 | 0.72 | CA12 (0.39) | EYA2APPACETDP1 | |
| SCHEMBL2467758 | 0.71 | TDP1 (0.52) | CYP1A2DPP4ZDHHC20EYA2APP | |
| SCHEMBL17666030 | 0.71 | — | — | |
| SCHEMBL20314817 | 0.71 | — | — | |
| SCHEMBL20314809 | 0.71 | ZDHHC20 (0.54) | CYP1A2DPP4ZDHHC20ZDHHC2 | |
| SCHEMBL3939074 | 0.69 | TDP1 (0.50) | CYP1A2DPP4ZDHHC20EYA2APP | |
| SCHEMBL16166221 | 0.68 | — | — | |
| SCHEMBL1725614 | 0.66 | MCL1 (0.39) | EYA2APPACETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669289-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
| EP-3201206-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-09-18 | — | — | EP | disclosed |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669289-B2 | Boronic acid derivatives | BCL9, BCL9L, BCL6 | CYP1A2 3721/4885DPP4 2071/4885ZDHHC20 3001/4885 |
| US-20180179232-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | CYP1A2 3721/4885DPP4 2071/4885ZDHHC20 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.