Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782293 | 0.81 | CTSS (0.35) | — | |
| SCHEMBL6448620 | 0.78 | TDP1 (0.36) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL30740904 | 0.77 | MVD (0.40) | MCL1TDP1EYA2APPACE | |
| SCHEMBL1405183 | 0.73 | LMNA (0.48) | MCL1KDM4ELMNATSHR | |
| SCHEMBL4943847 | 0.73 | LMNA (0.48) | MCL1KDM4ELMNATSHR | |
| SCHEMBL8015541 | 0.71 | MCL1 (0.39) | MCL1 | |
| Hydrochloric Acid SCHEMBL5796983 | 0.71 | LMNA (0.46) | MCL1KDM4ELMNATSHR | |
| SCHEMBL782292 | 0.70 | CTSS (0.35) | MCL1 | |
| SCHEMBL30536998 | 0.70 | — | — | |
| SCHEMBL30022145 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403829-A1 | CROSS-LINKING AGENTS | Centre National De La Recherche Scientifique CNRS (FR) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100238-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-09-10 | — | — | WO | disclosed |
| EP-2226314-A1 | Cross-linking agents | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) | 2010-09-08 | — | — | EP | disclosed |