Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037067 | 0.84 | KMT2A (0.72) | KMT2AATMGLASMN1; SMN2MAPK1 | |
| SCHEMBL6175746 | 0.83 | GLA (1.00) | KMT2AATMGLAPOLBSMN1; SMN2 | |
| SCHEMBL13133153 | 0.83 | KMT2A (0.70) | KMT2AATMGLAHPGDLMNA | |
| SCHEMBL15422991 | 0.81 | KMT2A (0.68) | KMT2AATMGLAPOLBSMN1; SMN2 | |
| SCHEMBL28586623 | 0.80 | GLA (0.74) | KMT2AATMGLAPOLBSMN1; SMN2 | |
| SCHEMBL56436 | 0.79 | ELANE (0.69) | KMT2AATMPOLBSMN1; SMN2HPGD | |
| SCHEMBL22258848 | 0.79 | KMT2A (0.65) | KMT2AATMGLALMNAELANE | |
| SCHEMBL23082631 | 0.77 | KMT2A (0.67) | KMT2AATMGLAPOLBSMN1; SMN2 | |
| SCHEMBL1767220 | 0.77 | GLA (0.70) | KMT2AATMGLAPOLBSMN1; SMN2 | |
| SCHEMBL16334971 | 0.74 | ELANE (0.68) | KMT2AATMGLAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| CN-111533668-A | Cyanostilbenes | 罗利克技术有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-3004050-A1 | CYANOSTILBENES | Rolic AG (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | KMT2A 3167/4885ATM 4135/4885GLA 3166/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | KMT2A 2902/4885ATM 1522/4885GLA 2858/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | KMT2A 2902/4885ATM 1522/4885GLA 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.