Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269820 | 0.88 | APP (0.35) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20320676 | 0.84 | TMEM97 (0.33) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13068305 | 0.83 | GAA (0.36) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1506800 | 0.83 | APP (0.35) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20346322 | 0.82 | APP (0.32) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5673675 | 0.80 | APP (0.33) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23193510 | 0.80 | APP (0.33) | APP | |
| SCHEMBL5674048 | 0.78 | HDAC1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13067887 | 0.78 | TMEM97 (0.36) | HDAC3HDAC1HDAC2 | |
| SCHEMBL7263798 | 0.77 | HDAC3 (0.33) | APPHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
| US-10717751-B2 | Near-IR glucose sensors | PROFUSA, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | ICMT 1004/4885APP 3950/4885MTNR1A 2602/4885 |
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | ICMT 1004/4885APP 3950/4885MTNR1A 2602/4885 |
| US-10717751-B2 | Near-IR glucose sensors | IRS1, G6PD, SLC2A8 | ICMT 1738/4885APP 3196/4885MTNR1A 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.