Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269820 | 0.93 | APP (0.35) | APPKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13068305 | 0.88 | GAA (0.36) | APPKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20346322 | 0.87 | APP (0.32) | APPKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20320676 | 0.86 | TMEM97 (0.33) | APPKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5673675 | 0.85 | APP (0.33) | APPKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL20320306 | 0.83 | ICMT (0.34) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5674048 | 0.83 | HDAC1 (0.42) | KDM4EHPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL13067887 | 0.82 | TMEM97 (0.36) | ALDH1A1HSD17B10LMNATP53SMN1; SMN2 | |
| SCHEMBL7263798 | 0.82 | HDAC3 (0.33) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1506801 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292626-B1 | Detection of analytes in aqueous environments | SENSEONICS INC (US) | 2014-05-21 | — | — | EP | claimed |
| EP-1557422-B1 | Detection of analytes in aqueous environments | SENSEONICS INC (US) | 2013-12-25 | — | — | EP | claimed |
| EP-1307464-B1 | DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS | SENSEONICS INC (US) | 2013-02-13 | — | — | EP | claimed |
| US-7939332-B2 | Detection of analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-05-10 | — | — | US | claimed |
| EP-2292626-A1 | Detection of analytes in aqueous environments | Sensors for Medicine and Science, Inc. (US) | 2011-03-09 | — | — | EP | claimed |
| WO-2007011691-A2 | IMPLANTABLE DEVICE FOR DETECTING AN ANALYTE IN VIVO | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2007-01-25 | — | — | WO | claimed |
| US-20070014726-A1 | Oxidation-resistant indicator macromolecule | SENSORS FOR MEDICINE AND SCIENCE (US) | 2007-01-18 | — | — | US | claimed |
| US-20060281185-A1 | Detection of analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2006-12-14 | — | — | US | claimed |
| US-7060503-B2 | Detection of Analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2006-06-13 | — | — | US | claimed |
| EP-1557422-A2 | Detection of analytes in aqueous environments | Sensors for Medicine and Science, Inc. (US) | 2005-07-27 | — | — | EP | claimed |
| US-20040229370-A1 | Detection of analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2004-11-18 | — | — | US | claimed |
| US-6794195-B2 | QUANTITATIVE, QUALITATIVE ANALYSIS | SENSORS FOR MEDICINE & SCIENCE, INC. | 2004-09-21 | — | — | US | claimed |
| US-6711423-B2 | Optical-based sensing devices | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2004-03-23 | — | — | US | claimed |
| EP-1307464-A1 | DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS | Sensors for Medicine and Science, Inc. (US) | 2003-05-07 | — | — | EP | claimed |
| US-20020039793-A1 | Detection of analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2002-04-04 | — | — | US | claimed |
| US-20020026108-A1 | Optical-based sensing devices | SENSEONICS, INCORPORATED | 2002-02-28 | — | — | US | claimed |
| WO-2002012251-A1 | DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2002-02-14 | — | — | WO | claimed |
| EP-2292626-B1 | Detection of analytes in aqueous environments | SENSEONICS INC (US) | 2014-05-21 | — | — | EP | disclosed |
| US-20020039793-A1 | Detection of analytes in aqueous environments | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2002-04-04 | — | — | US | disclosed |
| US-20020026108-A1 | Optical-based sensing devices | SENSEONICS, INCORPORATED | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070014726-A1 | Oxidation-resistant indicator macromolecule | MB, LPO, GPX4 | APP 1475/4885KDM4E 4434/4885ALDH1A1 112/4885 |
| US-20060281185-A1 | Detection of analytes in aqueous environments | MPI, NEFM, CD44 | APP 1144/4885KDM4E 4845/4885ALDH1A1 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.