Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 8/20 | 0.49 |
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823852 | 1.00 | MEN1 (0.69) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4820814 | 0.95 | MEN1 (0.76) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4820803 | 0.95 | MEN1 (0.76) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL2636479 | 0.88 | MEN1 (0.65) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL570909 | 0.88 | MEN1 (0.65) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL21056310 | 0.88 | MEN1 (0.65) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL19611471 | 0.87 | MEN1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL19611472 | 0.87 | MEN1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1764468 | 0.87 | MEN1 (0.63) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL9327481 | 0.87 | MEN1 (0.73) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256603-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117264925-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116601297-A | Modified helicase and application thereof | 北京齐碳科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-20250027130-A1 | Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-23 | — | — | US | disclosed |
| US-20240368568-A1 | MODIFIED PRP43 HELICASE AND USE THEREOF | QITAN TECHNOLOGY LTD., CHENGDU (CN) | 2024-11-07 | — | — | US | disclosed |
| CN-118256603-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-111534504-B | Method of ligating one or more polynucleotide binding proteins to a target polynucleotide | 牛津纳米孔科技公开有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118086476-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117965707-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117947148-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117947149-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20030119787-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | MEIJI SEIKA KAISHA LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| US-6576627-B1 | Such as 7-amino-2-((2-methyl-1-(3-phenylpropanoylamino)-propyl)hydroxyphosphinoyl) -methylheptanoic acid; thrombotic disease | MEIJI SEIKA KAISHA LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1152004-B1 | Phosphonic acid derivatives having carboxypeptidase B inhibitory action | MEIJI SEIKA KAISHA (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1174434-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | MEIJI SEIKA KAISHA LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-1152004-A1 | PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITORY ACTIVITY | MEIJI SEIKA KAISHA LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000044731-A1 | NOVEL HYDROXYAMIDINO CARBOXYLATE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000026195-A1 | NOVEL AMINO ACID HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-4900860-A | Process for preparing phosphonyloxyacyl amino acids | E. R. SQUIBB & SONS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4885380-A | REACTING PHOSPHONIC ACID DICHLORIDE WITH ALPHA-HYDROXY ACID TO FORM CYCLIC MIXED ANHYDRIDE; REACTING WITH AMINO ACID | THOTTATHIL JOHN K (US) | 1989-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119787-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | CPB1, RNPEP, CPN1 | MEN1 3845/4885KMT2A 2641/4885GAA 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.