SCHEMBL6823852

SCHEMBL6823852

CC(C)(C)OC(=O)NCCCC[C@H](O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
GAA P10253 1/20 0.69
TDP1 Q9NUW8 2/20 0.58
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
CA1 P00915 8/20 0.49
CA2 P00918 8/20 0.49
CA12 O43570 6/20 0.49
CA9 Q16790 6/20 0.49
GPR84 Q9NQS5 3/20 0.44
FFAR1 O14842 1/20 0.44
ATM Q13315 1/20 0.43
POLB P06746 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPT P10636 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2032033 1.00 MEN1 (0.69) MEN1KMT2AGAATDP1MAOA
SCHEMBL4820814 0.95 MEN1 (0.76) MEN1KMT2AGAATDP1MAOA
SCHEMBL4820803 0.95 MEN1 (0.76) MEN1KMT2AGAATDP1MAOA
SCHEMBL2636479 0.88 MEN1 (0.65) MEN1KMT2AGAATDP1MAOA
SCHEMBL570909 0.88 MEN1 (0.65) MEN1KMT2AGAATDP1MAOA
SCHEMBL21056310 0.88 MEN1 (0.65) MEN1KMT2AGAATDP1MAOA
SCHEMBL19611471 0.87 MEN1 (0.59) MEN1KMT2AGAATDP1MAOA
SCHEMBL19611472 0.87 MEN1 (0.59) MEN1KMT2AGAATDP1MAOA
SCHEMBL1764468 0.87 MEN1 (0.63) MEN1KMT2AGAATDP1MAOA
SCHEMBL9327481 0.87 MEN1 (0.73) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243472-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-07-31 US claimed
CN-118256603-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-06-28 CN claimed
CN-117264925-A Modified enzymes 牛津纳米孔科技公开有限公司 2023-12-22 CN claimed
CN-116601297-A Modified helicase and application thereof 北京齐碳科技有限公司 2023-08-15 CN claimed
US-20230212535-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-07-06 US claimed
EP-4198125-A2 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd., Beijing (CN) 2023-06-21 EP claimed
US-11525125-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-13 US claimed
EP-4063382-A9 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-11-16 EP claimed
EP-4063382-A1 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-09-28 EP claimed
US-20220290223-A1 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd. (CN) 2022-09-15 US claimed
US-20210009971-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2021-01-14 US claimed
EP-3575410-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2019-12-04 EP claimed
US-20180037874-A9 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2018-02-08 US claimed
US-20160257942-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2016-09-08 US claimed
EP-3058088-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2016-08-24 EP claimed
US-20150191709-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-07-09 US claimed
EP-2875128-A1 MODIFIED HELICASES Oxford Nanopore Technologies Limited (GB) 2015-05-27 EP claimed
WO-2015055981-A2 MODIFIED ENZYMES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-04-23 WO claimed
WO-2014013260-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-01-23 WO claimed
EP-4702157-A1 ACYL-TRNA SYNTHETASES United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
EP-4702156-A1 TRNA-BASED METHODS AND RELATED COMPOSITIONS United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
US-20250243472-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-07-31 US disclosed
US-12258591-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-03-25 US disclosed
CN-117264925-B Modified enzymes 牛津纳米孔科技公开有限公司 2025-03-21 CN disclosed
US-12252717-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-03-18 US disclosed
US-20250027130-A1 Nucleic Acid Synthesis and Sequencing Using Tethered Nucleoside Triphosphates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-23 US disclosed
US-20240417704-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-12-19 US disclosed
US-20240368568-A1 MODIFIED PRP43 HELICASE AND USE THEREOF QITAN TECHNOLOGY LTD., CHENGDU (CN) 2024-11-07 US disclosed
WO-2024223922-A1 ACYL-tRNA SYNTHETASES UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2024-10-31 WO disclosed
WO-2024223923-A1 tRNA-BASED METHODS AND RELATED COMPOSITIONS UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2024-10-31 WO disclosed
CN-114599666-B Pif1-like helicase and application thereof 北京齐碳科技有限公司 2024-08-06 CN disclosed
EP-4397970-A2 MUTANT PORE Oxford Nanopore Technologies PLC (GB) 2024-07-10 EP disclosed
CN-118256603-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-06-28 CN disclosed
CN-111534504-B Method of ligating one or more polynucleotide binding proteins to a target polynucleotide 牛津纳米孔科技公开有限公司 2024-06-21 CN disclosed
EP-4122949-B1 MUTANT PORE OXFORD NANOPORE TECH PLC (GB) 2024-06-05 EP disclosed
CN-118086476-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-05-28 CN disclosed
CN-117965707-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-05-03 CN disclosed
CN-117947149-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-04-30 CN disclosed
CN-117947148-A Modified enzymes 牛津纳米孔科技公开有限公司 2024-04-30 CN disclosed
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSTY (US) 2024-02-27 US disclosed
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSTY (US) 2024-02-27 US disclosed
US-20240026441-A1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE Oxford Nanopre Technologies PLC (GB) 2024-01-25 US disclosed
EP-4299746-A1 MODIFIED PRP43 HELICASE AND USE THEREOF Qitan Technology Ltd., Chengdu (CN) 2024-01-03 EP disclosed
CN-117264925-A Modified enzymes 牛津纳米孔科技公开有限公司 2023-12-22 CN disclosed
US-20230374567-A1 METHOD FOR MODIFYING A TEMPLATE DOUBLE STRANDED POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-11-23 US disclosed
WO-2023198911-A2 NOVEL MODIFIED PROTEIN PORES AND ENZYMES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-10-19 WO disclosed
WO-2023164676-A1 METHODS TO GENERATE NOVEL ACYL-TRNA SPECIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-31 WO disclosed
US-11725235-B2 Method for attaching one or more polynucleotide binding proteins to a target polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-15 US disclosed
CN-116601297-A Modified helicase and application thereof 北京齐碳科技有限公司 2023-08-15 CN disclosed
US-20230227799-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-07-20 US disclosed
US-20230212535-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-07-06 US disclosed
EP-4198125-A2 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd., Beijing (CN) 2023-06-21 EP disclosed
US-11649480-B2 Method for modifying a template double stranded polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-05-16 US disclosed
EP-4122949-A1 MUTANT PORE Oxford Nanopore Technologies plc (GB) 2023-01-25 EP disclosed
EP-4108679-A1 MODIFIED ENZYMES Oxford Nanopore Technologies plc (GB) 2022-12-28 EP disclosed
US-11525126-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-13 US disclosed
US-11525125-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-13 US disclosed
EP-4063382-A9 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-11-16 EP disclosed
EP-4063382-A1 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-09-28 EP disclosed
US-20220290223-A1 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd. (CN) 2022-09-15 US disclosed
EP-3204406-B1 MODIFIED ENZYMES OXFORD NANOPORE TECH PLC (GB) 2022-07-06 EP disclosed
US-20220162568-A1 PORE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-05-26 US disclosed
US-20220135956-A1 MODIFIED ENZYMES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2022-05-05 US disclosed
EP-3097210-B2 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECH LTD (GB) 2022-04-20 EP disclosed
EP-3953369-A1 PORE Oxford Nanopore Technologies plc (GB) 2022-02-16 EP disclosed
US-11180741-B2 Modified enzymes OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2021-11-23 US disclosed
CN-113677693-A Hole(s) 牛津纳米孔科技公司 2021-11-19 CN disclosed
US-20210123032-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-04-29 US disclosed
US-20210009971-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2021-01-14 US disclosed
EP-3464615-B1 METHOD OXFORD NANOPORE TECH LTD (GB) 2020-11-25 EP disclosed
EP-3741847-A1 MODIFIED HELICASES Oxford Nanopore Technologies Limited (GB) 2020-11-25 EP disclosed
US-20200360542-A1 SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY THE JOHNS HOPKINS UNIVERSTY 2020-11-19 US disclosed
US-20200360542-A1 SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY THE JOHNS HOPKINS UNIVERSTY 2020-11-19 US disclosed
US-10808231-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2020-10-20 US disclosed
WO-2020208357-A1 PORE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2020-10-15 WO disclosed
CN-111534504-A Methods of linking one or more polynucleotide binding proteins to a target polynucleotide 牛津纳米孔技术公司 2020-08-14 CN disclosed
US-10736974-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSITY (US) 2020-08-11 US disclosed
US-10736974-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSITY (US) 2020-08-11 US disclosed
US-10724018-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-07-28 US disclosed
US-20200087724-A1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-03-19 US disclosed
CN-106103741-B Methods of linking one or more polynucleotide binding proteins to a target polynucleotide 牛津纳米孔技术公司 2020-03-13 CN disclosed
EP-3575410-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2019-12-04 EP disclosed
US-10385389-B2 Method for attaching one or more polynucleotide binding proteins to a target polynucleotide OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2019-08-20 US disclosed
US-20190194722-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2019-06-27 US disclosed
EP-3464615-A1 METHOD Oxford Nanopore Technologies Limited (GB) 2019-04-10 EP disclosed
EP-3440098-A1 MUTANT PORE Oxford Nanopore Technologies Limited (GB) 2019-02-13 EP disclosed
EP-3097210-B1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECH LTD (GB) 2018-11-14 EP disclosed
US-20180037874-A9 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2018-02-08 US disclosed
WO-2017203267-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2017-11-30 WO disclosed
US-20170333576-A1 NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY THE JOHNS HOPKINS UNIVERSITY (US) 2017-11-23 US disclosed
US-20170333576-A1 NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY THE JOHNS HOPKINS UNIVERSITY (US) 2017-11-23 US disclosed
WO-2017174990-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2017-10-12 WO disclosed
EP-3204406-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2017-08-16 EP disclosed
US-20170107569-A1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2017-04-20 US disclosed
EP-3097210-A1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE Oxford Nanopore Technologies Limited (GB) 2016-11-30 EP disclosed
US-20160257942-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2016-09-08 US disclosed
EP-3058088-A2 MODIFIED ENZYMES Oxford Nanopore Technologies Limited (GB) 2016-08-24 EP disclosed
WO-2016055777-A2 MODIFIED ENZYMES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2016-04-14 WO disclosed
WO-2015110813-A1 METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-07-30 WO disclosed
US-20150191709-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-07-09 US disclosed
WO-2015055981-A2 MODIFIED ENZYMES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-04-23 WO disclosed
US-6737416-B2 THROMBOLYTIC AGENT HAVING HIGHER SAFETY MEIJI SEIKA KAISHA LTD. (JP) 2004-05-18 US disclosed
US-20030119787-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B MEIJI SEIKA KAISHA LTD. (JP) 2003-06-26 US disclosed
US-6576627-B1 Such as 7-amino-2-((2-methyl-1-(3-phenylpropanoylamino)-propyl)hydroxyphosphinoyl) -methylheptanoic acid; thrombotic disease MEIJI SEIKA KAISHA LTD. (JP) 2003-06-10 US disclosed
EP-1152004-B1 Phosphonic acid derivatives having carboxypeptidase B inhibitory action MEIJI SEIKA KAISHA (JP) 2003-05-07 EP disclosed
EP-1174434-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B MEIJI SEIKA KAISHA LTD. (JP) 2002-01-23 EP disclosed
EP-1152004-A1 PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITORY ACTIVITY MEIJI SEIKA KAISHA LTD. (JP) 2001-11-07 EP disclosed
US-4900860-A Process for preparing phosphonyloxyacyl amino acids E. R. SQUIBB & SONS, INC. (US) 1990-02-13 US disclosed
US-4885380-A REACTING PHOSPHONIC ACID DICHLORIDE WITH ALPHA-HYDROXY ACID TO FORM CYCLIC MIXED ANHYDRIDE; REACTING WITH AMINO ACID THOTTATHIL JOHN K (US) 1989-12-05 US disclosed
US-4885380-A REACTING PHOSPHONIC ACID DICHLORIDE WITH ALPHA-HYDROXY ACID TO FORM CYCLIC MIXED ANHYDRIDE; REACTING WITH AMINO ACID THOTTATHIL JOHN K (US) 1989-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030119787-A1 Phosphonic acid derivative having inhibitory activity against carboxypeptidase B CPB1, RNPEP, CPN1 MEN1 3845/4885KMT2A 2641/4885GAA 180/4885
US-20200360542-A1 SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY FOLH1, PSMA3, PSMA7 MEN1 844/4885KMT2A 3647/4885GAA 402/4885
US-11525126-B2 Modified helicases DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy FOLH1, PSMA3, PSMA7 MEN1 844/4885KMT2A 3647/4885GAA 402/4885
US-20240417704-A1 MODIFIED HELICASES DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885
US-10808231-B2 Modified helicases DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885
US-20210123032-A1 MODIFIED HELICASES DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885
US-12252717-B2 Modified helicases DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885
US-20170333576-A1 NEW SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY FOLH1, PSMA3, PSMA7 MEN1 1001/4885KMT2A 3946/4885GAA 605/4885
US-10736974-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy FOLH1, PSMA3, PSMA7 MEN1 844/4885KMT2A 3647/4885GAA 402/4885
US-20230227799-A1 MODIFIED HELICASES DDX21, DDX5, DDX17 MEN1 2969/4885KMT2A 2941/4885GAA 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.