SCHEMBL570909

SCHEMBL570909

CC(C)(C)OC(=O)NCC[C@H](O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.65
GAA P10253 1/20 0.65
KMT2A Q03164 1/20 0.65
TDP1 Q9NUW8 1/20 0.50
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
EPHX1 P07099 1/20 0.42
CTSS P25774 4/20 0.40
CTSK P43235 4/20 0.40
MALT1 Q9UDY8 1/20 0.40
IDO1 P14902 1/20 0.40
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KCNA5 P22460 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2636479 1.00 MEN1 (0.65) MEN1GAAKMT2ATDP1MAOA
SCHEMBL21056310 1.00 MEN1 (0.65) MEN1GAAKMT2ATDP1MAOA
SCHEMBL1764468 0.98 MEN1 (0.63) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4820803 0.90 MEN1 (0.76) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4820814 0.90 MEN1 (0.76) MEN1GAAKMT2ATDP1MAOA
SCHEMBL6823852 0.88 MEN1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL2032033 0.88 MEN1 (0.69) MEN1GAAKMT2ATDP1MAOA
SCHEMBL6915542 0.86 MEN1 (0.57) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4670568 0.86 MEN1 (0.56) MEN1GAAKMT2ATDP1MAOA
SCHEMBL15198752 0.86 MEN1 (0.56) MEN1GAAKMT2ATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110878108-B Synthetic method of prazazolmitrin 山东安信制药有限公司 2022-11-11 CN claimed
EP-3978506-B1 ANTIBACTERIAL AMINOGLYCOSIDE DERIVATIVES ZHUOHE PHARMACEUTICAL GROUP CO LTD (CN) 2025-10-22 EP disclosed
CN-120192356-A Prazomib preparation process of milnacipse 上海上药新亚药业有限公司 2025-06-24 CN disclosed
US-12338263-B2 Antibacterial aminoglycoside derivatives Zhuohe Pharmaceutical Group Co., Ltd (CN) 2025-06-24 US disclosed
US-20250163030-A1 PYRIDIZIN-3(2H)-ONE DERIVATIVES GILEAD SCIENCES, INC. 2025-05-22 US disclosed
CN-119350283-A Prazomycin impurity H and preparation method thereof 上海上药新亚药业有限公司 2025-01-24 CN disclosed
EP-4423078-A1 PYRIDIZIN-3(2H)-ONE DERIVATIVES GILEAD SCIENCES, INC. (US) 2024-09-04 EP disclosed
CN-118139858-A Pyrazin-3 (2H) -one derivatives 吉利德科学公司 2024-06-04 CN disclosed
EP-3891162-B1 NOVEL DERIVATIVES OF N-3\"-GUANIDINO-2,5-DIDEOXY-5-FLUORO-4,6-DISUBSTITUTED-STREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS AGILEBIOTICS B V (NL) 2024-03-06 EP disclosed
CN-116462721-B Antibacterial aminoglycoside derivative 江南大学 2024-02-02 CN disclosed
EP-1173472-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-23 EP disclosed
WO-2000064927-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 WO disclosed
EP-0546179-B1 4-O-(AMINOGLYCOSYL)- OR 4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXY-5,5-DIFLUOROSTREPTAMINE DERIVATIVE AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU (JP) 1997-02-12 EP disclosed
US-5527781-A AMINOGLYCOSIDE ANTIBIOTICS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1996-06-18 US disclosed
EP-0546179-A1 4-O-(AMINOGLYCOSYL)- OR 4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXY-5,5-DIFLUOROSTREPTAMINE DERIVATIVE AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1993-06-16 EP disclosed
EP-0259014-A2 5-Deoxy-5-fluorokanamycin B derivatives and processes for the production thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-03-09 EP disclosed
US-4410516-A 1-N(αHydroxy-ω-aminoalkanoyl) derivatives of 5,3',4'-trideoxy- or 5,3', 4'-trideoxy-6'-N- methyl- or 5, 3', 4',6\"-tetradeoxykannamyci B and production thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1983-10-18 US disclosed
US-4107424-A ANTIBACTERIAL ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1978-08-15 US disclosed
US-4001208-A DERIVATIVE OF AN AMINOGLYCOSIDIC ANTIBIOTIC ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYO KAI (JA) 1977-01-04 US disclosed
US-3940382-A BACTERICIDE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12338263-B2 Antibacterial aminoglycoside derivatives ATP6V1B1, ABCB11, RPN2 MEN1 4260/4885GAA 6/4885KMT2A 4247/4885
US-20250163030-A1 PYRIDIZIN-3(2H)-ONE DERIVATIVES PIR, CYP3A43, CYP1A2 MEN1 719/4885GAA 3136/4885KMT2A 2331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.