SCHEMBL20320600

SCHEMBL20320600

COC(=O)OC1C=C(C(C)(C)C)C(=O)N1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20320457 0.86 ELANE (0.31)
SCHEMBL20320501 0.84 POLB (0.33)
SCHEMBL20320438 0.83
SCHEMBL20320664 0.83 POLB (0.33)
SCHEMBL21610428 0.80 ALDH1A1 (0.32)
SCHEMBL20320437 0.79 CHRM2 (0.31)
SCHEMBL20320517 0.79 CASP3 (0.33) CYP1A2HIF1A
SCHEMBL20320661 0.79 CYP1A2 (0.36) CYP1A2HIF1A
SCHEMBL20320695 0.78 KDM4E (0.32) CYP1A2HIF1A
SCHEMBL20320507 0.78 ALOX5 (0.33) CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020002090-A1 SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2020-01-02 WO disclosed
WO-2020002091-A1 SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2020-01-02 WO disclosed
WO-2018114596-A1 SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-06-28 WO disclosed