Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20321107 | 0.84 | MAOA (0.45) | ALDH1A1SMN1; SMN2MAPTHPGDKDM4E | |
| SCHEMBL11912907 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL3346351 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL28530836 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL1232335 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8926474 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL851166 | 0.72 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL1982503 | 0.72 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL16894536 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8547015 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306166-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Aquinnah Pharmaceuticals Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-3557998-B1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2018119395-A1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |