Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74478 | 0.89 | NPSR1 (0.54) | SMN1; SMN2L3MBTL1MAPK1KDM4EKMT2A | |
| SCHEMBL27465 | 0.87 | DRD2 (0.62) | SMN1; SMN2DRD2DRD4L3MBTL1TDP1 | |
| SCHEMBL29381067 | 0.87 | DRD2 (0.62) | SMN1; SMN2DRD2DRD4L3MBTL1TDP1 | |
| SCHEMBL16672176 | 0.82 | NPSR1 (0.65) | L3MBTL1TDP1MAPK1KDM4EKMT2A | |
| SCHEMBL15509483 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD2DRD4L3MBTL1TDP1 | |
| SCHEMBL2063136 | 0.81 | DRD2 (0.72) | SMN1; SMN2DRD2DRD4L3MBTL1TDP1 | |
| SCHEMBL16838556 | 0.81 | HTT (0.40) | SMN1; SMN2L3MBTL1KDM4EKMT2AF2 | |
| SCHEMBL5686017 | 0.81 | DRD2 (0.72) | SMN1; SMN2DRD2DRD4L3MBTL1TDP1 | |
| SCHEMBL19384613 | 0.81 | KDM4E (0.51) | SMN1; SMN2L3MBTL1KDM4EKMT2ARAB9A | |
| SCHEMBL25944129 | 0.81 | KDM4E (0.60) | SMN1; SMN2L3MBTL1MAPK1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230152698-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| WO-2019148055-A9 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019148055-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-08-01 | — | — | WO | disclosed |
| WO-2018118598-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF FETAL LIVER KINASE POLYPEPTIDES | Arvinas, Inc. (US) | 2018-06-28 | — | — | WO | disclosed |