Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74478 | 0.93 | NPSR1 (0.54) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL1729519 | 0.87 | MAPK1 (0.75) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL14838113 | 0.85 | NPSR1 (0.46) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL14559903 | 0.83 | LMNA (0.48) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL13686326 | 0.83 | NPSR1 (0.50) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL18355078 | 0.83 | NPSR1 (0.47) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL20322452 | 0.82 | SMN1; SMN2 (0.52) | MAPK1L3MBTL1KMT2AALDH1A1TDP1 | |
| SCHEMBL10186609 | 0.81 | MAPK1 (0.68) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL10597796 | 0.81 | MAPK1 (0.68) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL3920395 | 0.81 | MAPK1 (0.68) | NPSR1MAPK1L3MBTL1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169904-A1 | SUBSTITUTED QUINOLINES AS IMPROVED NF-KB-INDUCING KINASE (NIK) INHIBITORS | Yukin Therapeutics (FR) | 2023-04-26 | — | — | EP | disclosed |
| US-9017918-B2 | Monomer, polymer, chemically amplified positive resist composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |