SCHEMBL74478

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16672176	0.93	NPSR1 (0.65)	NPSR1MAPK1KDM4EALDH1A1L3MBTL1
	SCHEMBL14559903	0.89	LMNA (0.48)	NPSR1MAPK1KDM4ENSD2ALDH1A1
	SCHEMBL18355078	0.89	NPSR1 (0.47)	NPSR1MAPK1KDM4ENSD2ALDH1A1
	SCHEMBL20322452	0.89	SMN1; SMN2 (0.52)	MAPK1KDM4EALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL19384613	0.87	KDM4E (0.51)	NPSR1KDM4EALDH1A1SMN1; SMN2L3MBTL1
	SCHEMBL25944129	0.87	KDM4E (0.60)	NPSR1MAPK1KDM4ENSD2ALDH1A1
	SCHEMBL75301	0.87	HPGD (0.41)	NPSR1MAPK1KDM4ENSD2ALDH1A1
	SCHEMBL9610288	0.86	NPSR1 (0.43)	NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL8170706	0.86	KDM4E (0.54)	NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL14118787	0.85	LMNA (0.50)	NPSR1MAPK1KDM4ENSD2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.