Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL203237 | 0.96 | TRPM8 (0.46) | TRPM8MAPK1HIF1AALDH1A1HPGD | |
| Benzoic Acid SCHEMBL203239 | 0.80 | TRPM8 (0.47) | TRPM8ALDH1A1HPGDKCNA5LMNA | |
| Menthol SCHEMBL28354486 | 0.78 | TRPM8 (0.51) | TRPM8ALDH1A1HPGDKCNA5LMNA | |
| SCHEMBL15433966 | 0.78 | TRPM8 (0.49) | TRPM8MAPK1ALDH1A1HPGDKCNA5 | |
| Menthyl Benzoate SCHEMBL3885473 | 0.76 | ALDH1A1 (0.69) | TRPM8MAPK1ALDH1A1HPGDLMNA | |
| Menthyl Benzoate SCHEMBL17407563 | 0.76 | ALDH1A1 (0.69) | TRPM8MAPK1ALDH1A1HPGDLMNA | |
| Menthyl Benzoate SCHEMBL18708099 | 0.76 | ALDH1A1 (0.69) | TRPM8MAPK1ALDH1A1HPGDLMNA | |
| Menthyl Benzoate SCHEMBL15498193 | 0.76 | ALDH1A1 (0.69) | TRPM8MAPK1ALDH1A1HPGDLMNA | |
| Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL28354549 | 0.75 | TRPM8 (0.48) | TRPM8MAPK1ALDH1A1HPGDKCNA5 | |
| SCHEMBL9292733 | 0.75 | TRPM8 (0.47) | TRPM8MAPK1ALDH1A1HPGDKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088872-B2 | Procatalyst composition including silyl ester internal donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2350144-A1 | PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD | Dow Global Technologies LLC (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010065361-A1 | PROCATALYST COMPOSITION INCLUDING SILYL ESTER INTERNAL DONOR AND METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | W. R. GRACE & CO.-CONN. | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130709-A1 | Procatalyst Composition Including Silyl Ester Internal Donor and Method | GNE, NANS, ELANE | TRPM8 4579/4885MAPK1 2989/4885HIF1A 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.