Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 14/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21637070 | 0.95 | TAS1R3 (0.47) | NT5ESTING1 | |
| SCHEMBL21637056 | 0.93 | NT5E (0.51) | NT5E | |
| SCHEMBL20324534 | 0.88 | STING1 (0.47) | NT5ESTING1 | |
| SCHEMBL20326954 | 0.88 | STING1 (0.47) | NT5ESTING1 | |
| SCHEMBL21636985 | 0.87 | POLB (0.48) | STING1POLB | |
| SCHEMBL21637066 | 0.87 | TAS1R3 (0.49) | NT5ESTING1 | |
| SCHEMBL21637057 | 0.83 | POLB (0.50) | STING1POLB | |
| SCHEMBL20326953 | 0.82 | STING1 (0.49) | NT5ESTING1POLB | |
| SCHEMBL20325358 | 0.82 | STING1 (0.49) | NT5ESTING1POLB | |
| SCHEMBL20326964 | 0.81 | RNASEL (0.48) | NT5ETGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |