Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 10/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20324525 | 0.92 | TGM2 (0.47) | TGM2NT5E | |
| SCHEMBL20324534 | 0.89 | STING1 (0.47) | NT5E | |
| SCHEMBL20326954 | 0.89 | STING1 (0.47) | NT5E | |
| SCHEMBL20324735 | 0.88 | RNASEL (0.62) | RNASEL | |
| SCHEMBL20324866 | 0.87 | RNASEL (0.55) | RNASEL | |
| SCHEMBL20326932 | 0.87 | STING1 (0.49) | TGM2NT5E | |
| SCHEMBL20324622 | 0.86 | STING1 (0.43) | NT5E | |
| SCHEMBL22080515 | 0.86 | RNASEL (0.56) | RNASEL | |
| SCHEMBL20327562 | 0.85 | RNASEL (0.56) | RNASEL | |
| SCHEMBL22352203 | 0.85 | RNASEL (0.59) | RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205323-A1 | STABLE FORMULATIONS OF CYCLIC DINUCLEOTIDE STING AGONIST COMPOUNDS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. (US) | 2020-10-08 | — | — | WO | disclosed |
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |