SCHEMBL20327586

Nc1nc2c(nnn2[C@H]2CC[C@@H](COP(=O)(O)O[C@H]3[C@@H](O)[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.58

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	13/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20324735	0.92	RNASEL (0.62)	RNASEL
SCHEMBL20324866	0.85	RNASEL (0.55)	RNASEL
SCHEMBL25400252	0.85	RNASEL (0.64)	RNASEL
SCHEMBL30084833	0.85	RNASEL (0.76)	RNASEL
SCHEMBL9951563	0.85	RNASEL (0.76)	RNASEL
SCHEMBL25402935	0.84	RNASEL (0.65)	RNASEL
SCHEMBL23061368	0.84	TAS1R3 (0.54)	RNASEL
SCHEMBL22352118	0.84	TAS1R3 (0.54)	RNASEL
SCHEMBL20327585	0.84	RNASEL (0.62)	RNASEL
SCHEMBL22352141	0.84	TAS1R3 (0.53)	RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018118665-A1	CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT	MERCK SHARP & DOHME CORP. (US)	2018-06-28	—	—	WO	disclosed