Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20324735 | 0.93 | RNASEL (0.62) | RNASEL | |
| SCHEMBL20327562 | 0.90 | RNASEL (0.56) | RNASEL | |
| SCHEMBL20325227 | 0.89 | RNASEL (0.54) | RNASEL | |
| SCHEMBL21540009 | 0.87 | TERT (0.53) | RNASEL | |
| SCHEMBL20325223 | 0.87 | TERT (0.53) | RNASEL | |
| SCHEMBL20782764 | 0.87 | TERT (0.53) | RNASEL | |
| SCHEMBL20324868 | 0.87 | TERT (0.53) | RNASEL | |
| SCHEMBL23061368 | 0.87 | TAS1R3 (0.54) | RNASEL | |
| SCHEMBL22352118 | 0.87 | TAS1R3 (0.54) | RNASEL | |
| SCHEMBL20326964 | 0.87 | RNASEL (0.48) | RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118664-A1 | COMBINATIONS OF PD-1 ANTAGONISTS AND CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |