Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309312 | 0.91 | FOS (0.49) | KDM4EHPGDTSHRCASP1CASP7 | |
| SCHEMBL20328556 | 0.87 | CYP2C9 (0.40) | ALDH1A1CYP2C9CYP2C19L3MBTL1POLB | |
| SCHEMBL17596186 | 0.85 | ALDH1A1 (0.46) | KDM4EHPGDTSHRCASP1CASP7 | |
| SCHEMBL17596508 | 0.84 | KDM4E (0.46) | KDM4EHPGDTSHRCASP1CASP7 | |
| SCHEMBL20328550 | 0.74 | POLB (0.44) | LMNAPOLB | |
| SCHEMBL18309310 | 0.74 | CYP2C9 (0.41) | ALDH1A1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL20328545 | 0.74 | AXL (0.43) | KDM4EHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1965857 | 0.71 | ALDH1A1 (0.78) | KDM4ETSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL3788631 | 0.71 | ALDH1A1 (0.49) | KDM4EHPGDTSHRCASP1CASP7 | |
| SCHEMBL1124253 | 0.70 | NR1H2 (0.68) | HSD17B10MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177190-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180177190-A1 | HERBICIDAL COMPOUNDS | DDT, CYP1B1, ATP1B1 | KDM4E 2198/4885HPGD 2779/4885TSHR 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.