Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309339 | 0.84 | MTNR1A (0.46) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22688050 | 0.84 | FOLH1 (0.36) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL20330623 | 0.83 | ALDH1A1 (0.34) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL18471059 | 0.83 | HDAC6 (0.34) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL22223342 | 0.83 | SMN1; SMN2 (0.44) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL22223343 | 0.83 | SMN1; SMN2 (0.44) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL12590064 | 0.82 | HTT (0.37) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL23642757 | 0.82 | ALDH1A1 (0.38) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL12972203 | 0.82 | ALDH1A1 (0.38) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL15759386 | 0.82 | ALDH1A1 (0.38) | HPGDHTTSMN1; SMN2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119196-A1 | IMMUNOCONJUGATES TARGETING ADAM9 AND METHODS OF USE THEREOF | IMMUNOGEN, INC. (US) | 2018-06-28 | — | — | WO | disclosed |