Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978666 | 0.88 | HTT (0.39) | HTTALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL12799291 | 0.83 | HTT (0.35) | HTTALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL16309339 | 0.83 | MTNR1A (0.46) | SMN1; SMN2LMNAL3MBTL1HDAC3HDAC4 | |
| SCHEMBL20330624 | 0.82 | HPGD (0.36) | HTTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12590065 | 0.82 | AKT1 (0.34) | HTTALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL18471059 | 0.82 | HDAC6 (0.34) | HTTSMN1; SMN2LMNAL3MBTL1HDAC3 | |
| SCHEMBL13950300 | 0.80 | SMN1; SMN2 (0.40) | HTTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL15934066 | 0.80 | MTNR1A (0.41) | HTTALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL18557387 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1HDAC3 | |
| SCHEMBL21389449 | 0.79 | ALDH1A1 (0.34) | HTTALDH1A1SMN1; SMN2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061080-B2 | HER2 binding peptides labeled with aluminium-[18] fluoride complexed by NOTA | GE HEALTHCARE LIMITED (GB) | 2015-06-23 | — | — | US | disclosed |
| US-20130295010-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | GE HEALTHCARE LIMITED (GB) | 2013-11-07 | — | — | US | disclosed |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2013-10-31 | — | — | US | disclosed |
| US-8487080-B2 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110160430-A1 | FLUORINE-LABELED COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | ERBB2, EGFR, ERBB3 | HTT 3163/4885ALDH1A1 4814/4885SMN1; SMN2 3269/4885 |
| US-20110160430-A1 | FLUORINE-LABELED COMPOUNDS | PFAS, DHFR, PAICS | HTT 1849/4885ALDH1A1 226/4885SMN1; SMN2 2305/4885 |
| US-20130295010-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | ERBB2, EGFR, ERBB3 | HTT 1569/4885ALDH1A1 4869/4885SMN1; SMN2 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.