Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530415 | 0.81 | LMNA (0.41) | LMNASMPD1ALDH1A1HSD17B10MEN1 | |
| Ethylene Glycol SCHEMBL2222341 | 0.77 | LMNA (0.44) | LMNASMPD1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL402782 | 0.75 | OPRM1 (0.41) | LMNASMPD1TSHRFDPSSPHK1 | |
| SCHEMBL821821 | 0.75 | OPRM1 (0.41) | LMNASMPD1TSHRFDPSSPHK1 | |
| SCHEMBL6692141 | 0.74 | SMPD1 (0.37) | SMPD1FDPSLAP3CA2 | |
| SCHEMBL11142939 | 0.73 | OPRM1 (0.42) | LMNASMPD1FDPSSPHK1TP53 | |
| SCHEMBL11614293 | 0.73 | SMPD1 (0.43) | LMNASMPD1FDPSSPHK1CYP2D6 | |
| SCHEMBL28382577 | 0.73 | LMNA (0.42) | LMNASMPD1ALDH1A1HSD17B10SPHK1 | |
| SCHEMBL5473642 | 0.72 | DNM1 (0.34) | TSHRFDPSSPHK1CA2 | |
| SCHEMBL29197496 | 0.72 | OPRM1 (0.38) | LMNASMPD1TSHRFDPSSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7959824-B2 | Refrigerating machine oil composition | NIPPON OIL CORPORATION (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20070032391-A1 | Refrigerating machine oil composition | NIPPON OIL CORPORATION (JP) | 2007-02-08 | — | — | US | disclosed |