Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033206 | 1.00 | TLR4 (0.34) | TLR4LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL12048501 | 0.89 | ALDH1A1 (0.33) | LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL13332165 | 0.89 | PKM (0.38) | LMNAMAPK1HTT | |
| SCHEMBL18922805 | 0.86 | TLR4 (0.35) | TLR4 | |
| SCHEMBL18922959 | 0.83 | TLR4 (0.31) | TLR4 | |
| SCHEMBL13072135 | 0.83 | TLR4 (0.34) | TLR4 | |
| SCHEMBL18922804 | 0.80 | TLR4 (0.33) | TLR4 | |
| SCHEMBL13361196 | 0.80 | TLR4 (0.38) | TLR4LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL7857566 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL13332135 | 0.79 | ALDH1A1 (0.37) | TLR4LMNAMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46426-E1 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-RE46426-E1 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9416317-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optical anisotropic body | LG CHEM, LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-9416317-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optical anisotropic body | LG CHEM, LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-20160024385-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICAL ANISOTROPIC BODY | LG CHEM, LTD. (KP) | 2016-01-28 | — | — | US | disclosed |
| US-20160024385-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICAL ANISOTROPIC BODY | LG CHEM, LTD. (KP) | 2016-01-28 | — | — | US | disclosed |
| US-9206355-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optically anisotropic body | LG CHEM, LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-9206355-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optically anisotropic body | LG CHEM, LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-20150115199-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICALLY ANISOTROPIC BODY | LG CHEM, LTD. (KR) | 2015-04-30 | — | — | US | disclosed |
| US-20150115199-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICALLY ANISOTROPIC BODY | LG CHEM, LTD. (KR) | 2015-04-30 | — | — | US | disclosed |
| US-20100222534-A1 | Mesogenic Dimers | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-02 | — | — | US | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| WO-2010020312-A1 | MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
| WO-2009039937-A1 | MESOGENIC DIMERS | MERCK PATENT GMBH (DE) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008119427-A1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1006098-B1 | Cross-bridged cyclohexane derivatives and liquid crystal medium | MERCK PATENT GMBH (DE) | 2004-04-07 | — | — | EP | disclosed |
| US-6303194-B1 | USED IN LIQUID-CRYSTAL AND ELECTRO-OPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT (DE) | 2001-10-16 | — | — | US | disclosed |
| US-6203724-B1 | FOR LIQUD CRYSTAL DISPLAYS, OPTICAL SWITCHES, OPTICAL FILTERS, ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-1006098-A2 | Cross-bridged cyclohexane derivatives and liquid crystal medium | MERCK PATENT GmbH (DE) | 2000-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222534-A1 | Mesogenic Dimers | PML, MLEC, MTX2 | TLR4 3280/4885LMNA 375/4885MAPK1 4429/4885 |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PUF60, LCP1, MAP1LC3C | TLR4 4020/4885LMNA 371/4885MAPK1 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.