Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20333119 | 0.92 | SUCNR1 (0.49) | MAPK8RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL20332700 | 0.81 | CYP2C9 (0.54) | RAB9ASMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL17066302 | 0.80 | NPC1 (0.62) | RAB9ASMN1; SMN2HTTLMNANPSR1 | |
| SCHEMBL20875961 | 0.80 | KMT2A (0.54) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2862442 | 0.79 | ALDH1A1 (0.60) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL23014236 | 0.79 | KDM4E (0.56) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL18083722 | 0.79 | HIF1A (0.69) | RAB9AMAPTHIF1AEPAS1KDM4E | |
| SCHEMBL20332850 | 0.79 | SUCNR1 (0.49) | RAB9ASMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL16346589 | 0.79 | HDAC1 (0.58) | SMN1; SMN2HTTLMNANPSR1HDAC1 | |
| SCHEMBL29769921 | 0.79 | RAB9A (0.54) | RAB9ASMN1; SMN2LMNANPSR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119362-A2 | HISTONE DEACETYLASE INHIBITORS | BIOMARIN PHARMACEUTICALS INC. (US) | 2018-06-28 | — | — | WO | disclosed |