SCHEMBL20334530

SCHEMBL20334530

CCOc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 7/20 0.36
BCAT2 O15382 5/20 0.36
KMT2A Q03164 2/20 0.33
PPOX P50336 2/20 0.33
MAT2A P31153 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SCN9A Q15858 1/20 0.32
MEN1 O00255 1/20 0.32
MAPK8 P45983 1/20 0.32
CYP3A4 P08684 1/20 0.32
UGCG Q16739 1/20 0.32
DRD1 P21728 1/20 0.32
BRD4 O60885 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
SSTR4 P31391 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2594502 0.92 BCAT1 (0.41) BCAT1BCAT2PPOXMAT2AMAPK8
SCHEMBL26017381 0.91 BCAT1 (0.35) BCAT1BCAT2PPOXMAT2AMAPK8
SCHEMBL121222 0.90 PPOX (0.41) BCAT1BCAT2KMT2APPOXALDH1A1
SCHEMBL29351496 0.90 PPOX (0.41) BCAT1BCAT2KMT2APPOXALDH1A1
Benzene SCHEMBL21843346 0.90 BCAT1 (0.34) BCAT1BCAT2KMT2AMAT2AMEN1
SCHEMBL1959750 0.90 BCAT1 (0.34) BCAT1BCAT2KMT2AMAT2AMEN1
SCHEMBL29709277 0.90 BCAT1 (0.34) BCAT1BCAT2KMT2AMAT2AMEN1
SCHEMBL12029834 0.90 UGCG (0.33) BCAT1BCAT2MAPK8CYP3A4UGCG
SCHEMBL22356179 0.90 UGCG (0.33) BCAT1BCAT2KMT2APPOXSCN9A
SCHEMBL21616077 0.89 PPOX (0.40) BCAT1BCAT2KMT2APPOXL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820755-B2 Uracil compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
US-11820755-B2 Uracil compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
US-20210122731-A1 URACIL COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-29 US disclosed
US-10966427-B2 3-pyridyl oxyanilide compound and use therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-06 US disclosed
US-20200120934-A1 3-PYRIDYL OXYANILIDE COMPOUND AND USE THEREFOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-04-23 US disclosed
WO-2020009193-A1 URACIL COMPOUND AND USE THEREOF 住友化学株式会社 2020-01-09 WO disclosed
WO-2018114759-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF Agro B.V. (NL) 2018-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210122731-A1 URACIL COMPOUND AND USE THEREOF UNG, UMPS, UGP2 BCAT1 243/4885BCAT2 278/4885KMT2A 1873/4885
US-20200120934-A1 3-PYRIDYL OXYANILIDE COMPOUND AND USE THEREFOR NOTUM, WEE2, WEE1 BCAT1 1081/4885BCAT2 1101/4885KMT2A 1331/4885
US-10966427-B2 3-pyridyl oxyanilide compound and use therefor NOTUM, WEE2, WEE1 BCAT1 1081/4885BCAT2 1101/4885KMT2A 1331/4885
US-11820755-B2 Uracil compound and use thereof UNG, UMPS, UGP2 BCAT1 243/4885BCAT2 278/4885KMT2A 1873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.