Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17191618 | 0.81 | GRM4 (0.33) | GRM4ROCK2ROCK1 | |
| SCHEMBL10261759 | 0.81 | GRM4 (0.33) | GRM4ROCK2ROCK1 | |
| SCHEMBL462660 | 0.81 | GRM4 (0.33) | GRM4ROCK2ROCK1 | |
| SCHEMBL19993506 | 0.78 | ALDH1A1 (0.38) | GRM4ROCK2ROCK1 | |
| SCHEMBL12809446 | 0.76 | — | — | |
| SCHEMBL22462729 | 0.76 | NOS3 (0.33) | ROCK2ROCK1 | |
| SCHEMBL8677451 | 0.76 | NOS3 (0.33) | ROCK2ROCK1 | |
| SCHEMBL5422 | 0.76 | — | — | |
| SCHEMBL25007747 | 0.75 | GRM4 (0.30) | GRM4 | |
| SCHEMBL21983611 | 0.74 | GRM4 (0.32) | GRM4ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284628-A1 | IRE1 SMALL MOLECULE INHIBITORS | CORNELL UNIVERSITY | 2021-09-16 | — | — | US | disclosed |
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284628-A1 | IRE1 SMALL MOLECULE INHIBITORS | XBP1, ERN2, ERN1 | GRM4 4586/4885ROCK2 2543/4885ROCK1 2973/4885 |
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | GRM4 4714/4885ROCK2 429/4885ROCK1 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.