SCHEMBL25007747

SCHEMBL25007747

CNC1CCCC(C(C)C)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18688068 0.95
SCHEMBL462660 0.93 GRM4 (0.33) GRM4
SCHEMBL10261759 0.93 GRM4 (0.33) GRM4
SCHEMBL17191618 0.93 GRM4 (0.33) GRM4
SCHEMBL24210496 0.82 SHBG (0.35)
SCHEMBL18881619 0.81 ADH1B (0.32)
SCHEMBL331741 0.79
SCHEMBL4390 0.79
SCHEMBL19121546 0.78
SCHEMBL14519164 0.78 ALDH1A1 (0.52) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023011446-A1 NOVEL SULFONAMIDE MENIN-MLL INTERACTION INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 成都苑东生物制药股份有限公司 2023-02-09 WO disclosed