SCHEMBL2033484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2030011	0.92	KIF11 (0.39)	KIF11MAPTNOTUMTUBB4ATUBB
	SCHEMBL2031707	0.92	MAPKAPK2 (0.40)	KIF11MAPTMAPKAPK2TP53LMNA
	SCHEMBL2030853	0.91	KIF11 (0.38)	KIF11MAPTMAPKAPK2TP53LMNA
	SCHEMBL2031790	0.90	CHRM4 (0.37)	MAPTNOTUMTUBB4ATUBBTUBA3C
	SCHEMBL2031298	0.89	MAPT (0.38)	KIF11MAPTTUBB4ATUBBTUBA3C
	SCHEMBL2032101	0.86	KDM4E (0.38)	KIF11MAPTTP53LMNAHPGD
	SCHEMBL2030005	0.86	KIF11 (0.42)	KIF11MAPTNOTUMMAPKAPK2ABCG2
	SCHEMBL2033551	0.86	KIF11 (0.47)	KIF11MAPTTP53ABCG2ABCB1
	SCHEMBL2036072	0.86	KIF11 (0.39)	KIF11MAPTNOTUMMAPKAPK2ABCG2
	SCHEMBL2030879	0.85	KIF11 (0.36)	KIF11MAPTMAPKAPK2TP53ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.