SCHEMBL20334904

SCHEMBL20334904

O=Nc1ccc(S(=O)(=O)c2ccc(Oc3ccc(S(=O)(=O)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 5/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ SOS1 Q07889 1/20 0.50
▸ HTR6 P50406 1/20 0.50
▸ LMNA P02545 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ PGR P06401 1/20 0.45
▸ MMP8 P22894 3/20 0.43
▸ MMP13 P45452 3/20 0.43
▸ MMP3 P08254 2/20 0.43
▸ MMP2 P08253 2/20 0.43
▸ MMP9 P14780 2/20 0.43
▸ MMP12 P39900 2/20 0.43
▸ MMP14 P50281 2/20 0.43
▸ MMP16 P51512 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ PKM P14618 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16810644 0.89 HTR6 (0.64) HTTSMN1; SMN2HTR6TDP1ALDH1A1
SCHEMBL6848913 0.87 HTT (0.74) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL20334751 0.85 HTT (0.51) HTTSMN1; SMN2SOS1LMNAL3MBTL1
SCHEMBL9323430 0.85 HTT (0.78) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL6123058 0.82 HTT (0.81) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL146566 0.82 HTT (0.81) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL11415437 0.82 HTT (0.81) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL17559302 0.82 HTT (0.81) HTTSMN1; SMN2SOS1HTR6LMNA
SCHEMBL10620953 0.82 LTA4H (0.57) HTTSOS1TDP1ALDH1A1CA1
Biphenyl SCHEMBL28423763 0.81 HTT (0.67) HTTSMN1; SMN2SOS1HTR6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220184469-A1 MULTI-PIECE GOLF CLUB HEAD TAYLOR MADE GOLF COMPANY, INC. 2022-06-16 — — US disclosed
US-10874914-B2 Golf club head TAYLOR MADE GOLF COMPANY, INC. (US) 2020-12-29 — — US disclosed
US-20180178092-A1 GOLF CLUB HEAD TAYLOR MADE GOLF COMPANY, INC. 2018-06-28 — — US disclosed
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