SCHEMBL20335121

SCHEMBL20335121

CCOC(=O)C(Cc1ccccc1)NC(=O)NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.69
F2 P00734 6/20 0.59
PRSS1 P07477 6/20 0.59
PRSS2 P07478 6/20 0.59
PRSS3 P35030 6/20 0.59
CTSL P07711 1/20 0.56
ATM Q13315 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MMP9 P14780 2/20 0.53
MMP1 P03956 1/20 0.53
MMP2 P08253 1/20 0.53
MMP8 P22894 1/20 0.53
LMNA P02545 1/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
POLB P06746 1/20 0.49
BACE1 P56817 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20335120 1.00 GAA (0.69) GAAF2PRSS1PRSS2PRSS3
SCHEMBL20335002 0.92 GAA (0.70) GAAF2PRSS1PRSS2PRSS3
SCHEMBL20335001 0.92 GAA (0.70) GAAF2PRSS1PRSS2PRSS3
SCHEMBL20335036 0.88 GAA (0.75) GAAF2PRSS1PRSS2PRSS3
SCHEMBL20335034 0.88 GAA (0.75) GAAF2PRSS1PRSS2PRSS3
SCHEMBL20335042 0.86 GAA (0.72) GAAF2PRSS1PRSS2PRSS3
SCHEMBL28216943 0.84 MMP8 (0.53) GAAATML3MBTL1MMP9MMP1
SCHEMBL12149993 0.82 POLB (0.63) GAACTSLATML3MBTL1MMP8
Tosifen SCHEMBL29387539 0.82 GAA (1.00) GAAF2PRSS1PRSS2PRSS3
Tosifen SCHEMBL1133723 0.82 GAA (1.00) GAAF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 GAA 4169/4885F2 2862/4885PRSS1 2184/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 GAA 4231/4885F2 2730/4885PRSS1 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.