SCHEMBL20335136

SCHEMBL20335136

Cc1cccc(NC(=O)NC(CC(C)C)C(=O)NC(C)C(=O)O)c1

nearest known ligand 0.78

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.60
TP53 P04637 1/20 0.57
CCKBR P32239 1/20 0.55
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53
MMP2 P08253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20335134 1.00 MAPK1 (0.60) MAPK1TP53CCKBRMEN1MAPT
SCHEMBL28779256 0.85 SMN1; SMN2 (0.66) MEN1MAPTKMT2A
SCHEMBL29771178 0.85 SMN1; SMN2 (0.66) MEN1MAPTKMT2A
SCHEMBL27133210 0.85 SMN1; SMN2 (0.66) MEN1MAPTKMT2A
SCHEMBL14889619 0.79 FPR2 (0.78)
SCHEMBL19723124 0.79 FPR2 (0.78)
SCHEMBL20335086 0.77 SMN1; SMN2 (0.53) MEN1MAPTKMT2A
SCHEMBL29776982 0.77 SMN1; SMN2 (0.53) MEN1MAPTKMT2A
SCHEMBL20335091 0.77 SMN1; SMN2 (0.53) MEN1MAPTKMT2A
SCHEMBL13765047 0.76 FPR2 (0.60) MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 MAPK1 454/4885TP53 3780/4885CCKBR 896/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 MAPK1 377/4885TP53 3543/4885CCKBR 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.