Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20336531 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EAOC3CNR2SLC6A4 | |
| SCHEMBL20336549 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EAOC3CNR2SLC6A4 | |
| SCHEMBL22040557 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4ECNR2SLC6A4SLC6A3 | |
| SCHEMBL17894178 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4ECNR2SLC6A4SLC6A3 | |
| SCHEMBL20336627 | 0.81 | RCE1 (0.45) | ALDH1A1KDM4ECNR2SLC6A4SLC6A3 | |
| SCHEMBL20336625 | 0.81 | RCE1 (0.45) | ALDH1A1KDM4ECNR2SLC6A4SLC6A3 | |
| SCHEMBL21587147 | 0.76 | IDO1 (0.48) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20463639 | 0.75 | RCE1 (0.49) | ALDH1A1AOC3SLC6A4SLC6A3MMP9 | |
| SCHEMBL5018878 | 0.75 | RCE1 (0.49) | ALDH1A1AOC3SLC6A4SLC6A3MMP9 | |
| SCHEMBL20837594 | 0.75 | SLC6A4 (0.45) | ALDH1A1KDM4ESLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-110352006-B | Picolinamides as fungicides | 美国陶氏益农公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-3565410-A1 | PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2019-11-13 | — | — | EP | disclosed |
| US-10246417-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018129238-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129237-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885KDM4E 2568/4885AOC3 1260/4885 |
| US-10246417-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885KDM4E 2568/4885AOC3 1260/4885 |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885KDM4E 2568/4885AOC3 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.