Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562131 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDDDB1CRBNCHRM1 | |
| SCHEMBL10562127 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDDDB1CRBNCHRM1 | |
| SCHEMBL2009724 | 0.74 | ALDH1A1 (0.47) | RIPK1ALDH1A1DDB1CRBNPKM | |
| SCHEMBL2009722 | 0.74 | ALDH1A1 (0.47) | RIPK1ALDH1A1DDB1CRBNPKM | |
| SCHEMBL10860547 | 0.69 | CHRM1 (0.47) | ALDH1A1DDB1CRBNCHRM1 | |
| SCHEMBL10713076 | 0.69 | NAMPT (0.55) | ALDH1A1HPGDDDB1CRBNNPSR1 | |
| SCHEMBL18196121 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HPGDDDB1CRBNNPSR1 | |
| SCHEMBL2399783 | 0.67 | NPSR1 (0.49) | HPGDCHRM1NPSR1CARM1PRMT6 | |
| SCHEMBL18286474 | 0.66 | CARM1 (0.72) | NPSR1CARM1PRMT6 | |
| SCHEMBL11525757 | 0.66 | MEN1 (0.49) | ALDH1A1HPGDDDB1CRBNPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507230-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067272-A1 | INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |