Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275706 | 0.77 | ALDH1A1 (0.46) | ALDH1A1DDB1CRBNHTTHPGD | |
| SCHEMBL16579918 | 0.74 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBNMEN1KMT2A | |
| SCHEMBL10454044 | 0.74 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBNMEN1KMT2A | |
| SCHEMBL7039408 | 0.70 | DDB1 (0.52) | ALDH1A1DDB1CRBNHTTPKM | |
| SCHEMBL11903535 | 0.68 | DDB1 (0.65) | ALDH1A1DDB1CRBNHTTPKM | |
| SCHEMBL15014140 | 0.68 | MEN1 (0.61) | NPSR1HPGDCARM1PRMT6NPC1 | |
| SCHEMBL20740124 | 0.68 | ALDH1A1 (0.51) | ALDH1A1DDB1CRBNHTTPKM | |
| SCHEMBL18387872 | 0.68 | MEN1 (0.61) | NPSR1HPGDCARM1PRMT6NPC1 | |
| SCHEMBL15014137 | 0.68 | MEN1 (0.61) | NPSR1HPGDCARM1PRMT6NPC1 | |
| SCHEMBL10562127 | 0.68 | ALDH1A1 (0.48) | ALDH1A1DDB1CRBNHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790181-B2 | Method for producing 5-hydroxypiperidine-2-carboxylic acid | API CORPORATION (JP) | 2017-10-17 | — | — | US | disclosed |
| EP-3091002-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API Corporation (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-20160318867-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | API CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318867-A1 | METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID | HPD, ADCY5, CYP2A7 | ALDH1A1 132/4885DDB1 4766/4885CRBN 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.