SCHEMBL20338043

SCHEMBL20338043

CCN(CC)CCNC(=O)c1ccc2cc(OC(N)=O)ccc2n1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 16/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SCN10A Q9Y5Y9 2/20 0.46
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29472460 0.82 ALDH1A1 (0.58) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL13426298 0.82 ALDH1A1 (0.51) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL15840356 0.82 ALDH1A1 (0.58) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL14310903 0.81 ACKR3 (0.53) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL19636619 0.81 TERT (0.48) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL2444201 0.80 ALDH1A1 (0.51) SCN9AMEN1KMT2AALDH1A1KDM4E
Hydrochloric Acid SCHEMBL2447950 0.79 ALDH1A1 (0.50) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL19633172 0.78 ALDH1A1 (0.49) SCN9AMEN1KMT2AALDH1A1KDM4E
SCHEMBL19611848 0.77 TERT (0.49) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL28813505 0.77 ALDH1A1 (0.68) MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213394-B Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-11-08 CN claimed
CN-114213394-A Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-03-22 CN claimed
CN-114213394-B Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-11-08 CN disclosed
CN-114213394-B Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-11-08 CN disclosed
US-11371996-B2 Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same WATERS TECHNOLOGIES CORPORATION (US) 2022-06-28 US disclosed
CN-114213394-A Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-03-22 CN disclosed
CN-114213394-A Synthesis method of N-sugar analysis reagent fluorogenic substrate 上海瀚诺威生物科技有限公司 2022-03-22 CN disclosed
US-20180188259-A1 METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME WATERS TECHNOLOGIES CORPORATION (US) 2018-07-05 US disclosed